Universal reference book for medicines
Product name: DAIVONEX ® (DAIVONEX)

Active substance: calcipotriol

Type: Antiproliferative drug for the treatment of psoriasis

Manufacturer: LEO Pharmaceutical Products Ltd.
A / S (LEO Pharma A / S) (Denmark)
Description of the active substance:
This information is a reference and it is not enough that the drug was prescribed by a doctor.
.
PHARMACHOLOGIC EFFECT
Synthetic analogue of the most active metabolite of natural vitamin D 3 .
Causes a dose-dependent inhibition of the proliferation of keratinocytes (significantly elevated in patients with psoriasis) and accelerates their morphological differentiation. Has an insignificant effect on the metabolism of calcium in the body.
INDICATIONS
Psoriasis.

DOSING MODE
Apply externally to the affected skin 2 times / day.
The maximum daily dose is 15 g, and the weekly - 100 g. Usually, the therapeutic effect develops within 1-2 weeks of treatment. The duration of the course of therapy is no more than 6-8 weeks.
SIDE EFFECT
In some cases: transient skin irritation;
when used in doses exceeding the recommended - hypercalcemia.
CONTRAINDICATIONS
Hypersensitivity to calcipotriol.

PREGNANCY AND LACTATION
Not recommended for use in pregnancy.

APPLICATION FOR CHILDREN
Children are used with caution.

SPECIAL INSTRUCTIONS
Do not apply on the face.
Children are used with caution.
Do not use together with salicylic acid preparations for external use.

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