Universal reference book for medicines
Product name: HEXALYSIS (HEXALYSE)

Active substance: biclotymol, enoxolone, lysozyme

Type: The drug with antimicrobial and anti-inflammatory action for topical application in ENT practice and dentistry

Manufacturer: Laboratoires BOUCHARA-RECORDATI (France)
Composition, form of production and packaging
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Tablets for resorption of yellow-orange color, round, flat-cylindrical, with a facet, with a weak characteristic odor; may be orange or white.
1 tab.

biclutimol 5 mg

lysozyme hydrochloride 5 mg

enoxolone 5 mg

Auxiliary substances: lemon oil - 200 mcg, citric acid monohydrate - 10 mg, dye sunset yellow (E110) - 100 mcg, magnesium stearate - 15 mg, acacia gum - 60 mg, sucrose - up to 1200 mg.

10 pieces.
- blisters (3) - packs of cardboard.
INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2014.

PHARMACHOLOGIC EFFECT

Combination drug for topical application with antimicrobial, antiviral and anti-inflammatory action.

Biklotimol is an antiseptic.
It is active against staphylococci, streptococci and corynebacteria, has a local anesthetic and anti-inflammatory effect. When topical application is characterized by prolonged action.
Lysozyme is a polypeptide mucolytic enzyme that has an antimicrobial effect.
It is active against gram-positive bacteria, gram-negative microorganisms are less sensitive to lysozyme. Promotes an increase in the activity of nonspecific factors of body defense, has anti-inflammatory and mucolytic effects. Lysozyme exhibits antiviral activity (it forms complexes with viruses). Refers to natural factors of body protection.
Enoxolone is a complex triterpen, isolated from glycyrrhizic acid.
Inhibits 11-beta-hydroxysteroid dehydrogenase, inactivating cortisol. Has anti-inflammatory, antimicrobial and antiviral effects.
PHARMACOKINETICS

Studies of the pharmacokinetics of Hexalysis have not been conducted.

INDICATIONS

For local treatment of infectious and inflammatory diseases of the oral, pharyngeal and laryngeal mucosa caused by microorganisms sensitive to biclutymol, lysozyme and enoxolone:

- Acute and chronic pharyngitis;

- pharyngolaringitis;

- tonsillitis;

- conditions after tonsillectomy;

glossitis.

DOSING MODE

Adults appoint 1 tablet.
every 2 hours. The maximum dose is 8 tablets / day.
Children over 6 years of age are prescribed 1 tab.
every 4 hours.
The duration of treatment should not exceed 10 days.

Tablets must be resorbed until completely dissolved.

SIDE EFFECT

Possible: allergic reactions, superinfection;
with prolonged use (more than 10 days) - dysbacteriosis of the oral cavity with the risk of spread of bacterial and fungal infection.
CONTRAINDICATIONS

- children's age till 6 years;

- Hypersensitivity to the components of the drug.

PREGNANCY AND LACTATION

During pregnancy and lactation (breastfeeding), Hexalysis is prescribed only according to strict indications.

APPLICATION FOR CHILDREN

Contraindication: children under 6 years.

SPECIAL INSTRUCTIONS

When prescribing a patient with diabetes, it is necessary to take into account that 1 tablet contains 1.054 g of sugar.

If the therapeutic effect is absent or weak within 5 days, the therapy should be reviewed.

OVERDOSE

At present, cases of overdose of Hexalisis have not been reported.

DRUG INTERACTION

It is necessary to avoid simultaneous use of other medications for topical application in the oral cavity.

TERMS OF RELEASE FROM PHARMACY

The drug is approved for use as a means of OTC.

TERMS AND CONDITIONS OF STORAGE

The drug should be stored out of the reach of children at a temperature of no higher than 25 ° C.
Shelf life - 2 years.
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