Universal reference book for medicines
Product name: VALOCORDIN ® (VALOCORDIN)

Active substance: ethyl alpha-bromoisovalerate, phenobarbital

Type: The drug with sedative and spasmolytic action

Manufacturer: KREWEL MEUSELBACH (Germany)
Composition, form of production and packaging
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Drops for ingestion in the form of a transparent, colorless liquid with a fragrant odor.
1 ml

phenobarbital 18.4 mg

ethyl bromoisovalerianate 18.4 mg

Excipients: mint oil - 1.29 mg, hop oil - 0.18 mg, ethanol 96% - 469.75 mg, purified water - 411.97 mg.

20 ml - a bottle of a dropper of dark glass (1) - packs cardboard.

50 ml - a bottle of a dropper of dark glass (1) - packs cardboard.

INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2016.

PHARMACHOLOGIC EFFECT

Valocordin - a combined drug, the therapeutic effect of which is due to the pharmacological properties of the components that make up its composition.
Phenobarbital has sedative and vasodilating effect, and also has a mild hypnotic effect. Helps reduce the excitation of the central nervous system and facilitates the onset of natural sleep.
Ethyl bromizovalerianate has a sedative, hypnotic and spasmolytic effect.

INDICATIONS

- Functional disorders of the cardiovascular system (including cardialgia, sinus tachycardia);

- neuroses accompanied by irritability, anxiety, fear;

- Insomnia (difficulty falling asleep);

- Excitation conditions, accompanied by pronounced vegetative reactions.

DOSING MODE

Valokordin is taken orally, before meals, with a small amount of liquid.
Dosage is set individually.
Adults usually appoint 15-20 drops 3 times / day.

With disturbed sleep, the dose can be increased to 30 drops.

The duration of the drug is determined individually by the doctor.

SIDE EFFECT

Valocordin ® , as a rule, is well tolerated even with prolonged use.

In some cases, during the daytime, drowsiness and light dizziness may occur.

With prolonged use of large doses, it is possible to develop chronic bromine poisoning, which manifestations include: depressive mood, apathy, rhinitis, conjunctivitis, hemorrhagic diathesis, disruption of coordination of movements.

Rarely, with increased sensitivity, skin reactions may occur.

If any side effects are observed that are not reflected in the instructions, it is necessary to inform the treating doctor about them.

CONTRAINDICATIONS

- pronounced impairment of renal and / or liver function;

- Pregnancy,

- lactation period;

- children's age till 18 years;

- Hypersensitivity to any of the components of the drug.

With co-generation

Diseases of the liver, alcoholism, craniocerebral trauma, brain diseases, tk.
the preparation contains ethanol.
APPLICATION FOR FUNCTIONS OF THE LIVER

Contraindicated in severe impairment of kidney function.

APPLICATION FOR VIOLATIONS OF THE FUNCTION OF KIDNEYS

With caution, take the drug to patients with liver disease.

Contraindicated in severe violations of liver function.

APPLICATION FOR CHILDREN

Contraindicated use of the drug for children and adolescents under the age of 18 years.

SPECIAL INSTRUCTIONS

If it is necessary to prescribe the drug during lactation, the question of stopping breastfeeding should be solved.

The preparation contains 55% by volume of ethanol (absolute content of ethanol in the maximum single dose (30 drops) is 0.469 g) and phenobarbital, therefore, with proper application, Valocordin ® can weaken the ability of patients to react quickly in certain situations, such as when on the street or when servicing machines.
This is particularly pronounced when taking alcohol at the same time.
With prolonged use of the drug, the formation of drug dependence is possible;
Possible the accumulation of bromine in the body and the development of poisoning them.
OVERDOSE

Symptoms: with mild to moderate intoxication, drowsiness, dizziness, psychomotor disorders are observed.
In severe cases - coma, lowering blood pressure, respiratory failure, tachycardia, vascular collapse, decreased peripheral reflexes.
Treatment: rinse the stomach, take activated charcoal and urgently call a doctor.

DRUG INTERACTION

With the simultaneous use of Valocordinum with sedatives, the effect is markedly enhanced.

Simultaneous use with neuroleptics and tranquilizers increases, and with stimulants of the CNS - weakens the effect of each of the components of the drug.

Alcohol enhances the effects of Valocordin and can increase its toxicity.

The presence of phenocarbital in Valocordin can induce liver enzymes, and this makes it undesirable to use it simultaneously with drugs that are metabolized in the liver, as their concentration, and accordingly, the effectiveness will decrease as a result of more accelerated metabolism (indirect anticoagulants, antibiotics, sulfonamides, etc.). .

Phenobarbital weakens the action of coumarin derivatives, GCS, griseofulvin, oral contraceptives.

TERMS OF RELEASE FROM PHARMACY

The drug is approved for use as a means of OTC.

TERMS AND CONDITIONS OF STORAGE

The drug should be stored in a place protected from light and inaccessible to children at a temperature of 15 ° to 25 ° C.
Shelf life - 5 years.
Do not use after the expiration date printed on the package.

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