Universal reference book for medicines
Product name: VACCINE LIVING PLANE (LIVE PLAGUE VACCINE)

Active substance: nonappropriate

Type: Vaccine for the prevention of plague

Producer: 48 CSRI MINISTRY OF RUSSIA FGU (Russia)
Composition, form of production and packaging
Tablets for resorption of
light brown color, regular round shape, with integral edges, flat and flat surface;
has the smell of cocoa, vanillin and menthol.
1 tab.

lyophilized live culture of the vaccine strain of the plague microbe Yersinia pestis EV line NIIEG (40 ± 10) × 10 9 live microbes

Excipients: dextrin 6 mg, ascorbic acid 6 mg, lactose 60 mg, thiourea 6 mg, vanillin 2 mg, glucose 0.44 g, cocoa powder 11.4 mg, calcium stearate 12 mg, potato starch 11.4 mg, menthol 2.2 mg, saccharin 1.1 mg .

40 pcs.
- banks of dark glass (1) - packs of cardboard.
90 pcs.
- banks of dark glass (1) - packs of cardboard.
INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2014.

PHARMACHOLOGIC EFFECT

The vaccine causes vaccines to develop immunity to a plague lasting up to 1 year.

INDICATIONS

- prevention of plague.

Vaccinations are subject to:

- population from 14 years of age living in enzootic plague territories;

- persons working with live cultures of the causative agent of the plague, infected with laboratory animals, conducting a study of the material suspected of being infected with the causative agent of the plague.

DOSING MODE

One inoculation dose is one tablet.
Vaccination is carried out once by taking one tablet, which must be actively resorbed or thoroughly chewed for 5-7 minutes.
Swallowing the tablet is strictly prohibited!

After taking the pill for 30 minutes, it is not recommended to drink, eat, smoke.

Revaccination is carried out after one year (in unfavorable epidemics - after 6 months) with the same dose.

Before the vaccine is used, the integrity of the package, the presence of labels on the cans, the appearance of the tablets are monitored.
Unsuitable is the drug in a container with broken integrity, with a changed appearance (tablets with uneven edges, cracks and spots), expired, no labels or missing information on them.
SIDE EFFECT

Inoculations with the vaccine can be accompanied by both local and general reactions.

Local reactions are manifested in the form of limited, mild hyperemia of the oral mucosa in the tonsils and minor pain experienced during swallowing.
Local reactions occur 1-3 days after vaccination and last for 2-3 days.
Common reactions can be mild, moderate and severe and are accompanied by an increase in body temperature, malaise, headache, weakness, pain in the muscles.

Weak reaction - an increase in body temperature to 37.1-37.5 ° C with a duration of 1-2 days, should be observed no more than 3% of cases.

The average is an increase in body temperature to 37.6-38.5 ° C with a duration of 1-2 days, a total loss of ability to work no more than 1 day.
The average reaction should be observed in no more than 2% of cases.
Strong - an increase in body temperature above 38.5 ° C lasting 1-3 days, a total loss of ability to work more than 1 day.
A strong reaction should be observed in no more than 1% of cases.
CONTRAINDICATIONS

- acute infectious and non-infectious diseases, chronic diseases at the stage of exacerbation - vaccinations are given no earlier than 1 month after recovery (remission);

- Primary and secondary immunodeficiencies.
In the treatment of steroids, antimetabolites, chemo- and roentgenotherapy - vaccinations are given no earlier than 6 months after the end of treatment.
- systemic connective tissue diseases;

- malignant neoplasms and malignant diseases of the blood;

- diseases of the endocrine system;

- allergic diseases (bronchial asthma, anaphylactic shock, Quincke's edema in the anamnesis);

- pregnancy and lactation.

In each individual case for diseases not included in this list, vaccination is carried out only with the permission of the appropriate specialist doctor.

In order to identify contraindications, the doctor (paramedic) on the day of vaccination conducts a survey and examination of the vaccine with mandatory thermometry.

PREGNANCY AND LACTATION

Contraindicated in pregnancy and lactation.

APPLICATION FOR CHILDREN

Applied in children older than 14 years.

OVERDOSE

In recommended doses, an overdose is not possible.

DRUG INTERACTION

Simultaneous oral vaccination of adults against plague and cutaneous versus brucellosis and tularemia in different parts of the outer surface of the upper third of the shoulder is allowed.

The vaccine is sensitive to antibiotics, and therefore immunization against the background of antibiotics is not allowed.

TERMS OF RELEASE FROM PHARMACY

For treatment and preventive and sanitary facilities.

TERMS AND CONDITIONS OF STORAGE

Store in accordance with SP 3.3.2.1248-03 at a temperature of 0 to 8 ° C, out of reach of children.

Transport in accordance with SP 3.32.1248-03 at a temperature of 0 to 8 ° C.

Shelf life 1 year.
The drug with expired shelf life is not subject to application.
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