Universal reference book for medicines
The name of the preparation: VACCINE VAPCINE MEASLES-MUMPS CULTURE LIVE (VACCINE MEASLES-MUMPS CULTURE LIVE)

Active substance: gentamicin, measles vaccine (live), mumps vaccine (live)

Type: Vaccine for the prevention of measles and mumps

Producer: NGO MIKROGEN (Russia)
A typical clinical and pharmacological article
This information is a reference and it is not enough that the drug has been prescribed by a doctor ..

PHARMACHOLOGIC EFFECT
Stimulates the production of antibodies to measles and mumps virus at 3-4 weeks and 6-7 weeks, respectively, after vaccination.

INDICATIONS
Prevention of measles and mumps: primary - in children aged 12 months and 6 years, not infected with measles and mumps, emergency - in children from 12 months and adults who had contact with a patient with measles or mumps, not infected with these infections and not vaccinated against them (no later than 72 hours after contact with the patient, in the absence of contraindications).

DOSING MODE
A scapula under the shoulder blade or shoulder area (on the border between the lower and middle third of the shoulder from the outside), once in a dose of 0.5 ml.

SIDE EFFECT
From 4 to 18 days after the introduction of the vaccine: hyperthermia (in case of mass vaccination, an increase in body temperature above 38.5 degrees C should not be more than 2% of vaccinated children), catarrhal phenomena (hyperemia of the throat, rhinitis), lasting 1-3 days;
rarely - a short-term (2-3 days) insignificant increase in parotid salivary glands (the general condition is not violated at the same time), malaise, korepodobnaya rash.

Local reactions: insignificant skin hyperemia and soft tissue edema, which pass through 1-3 days without treatment.


Rarely - allergic reactions (in the first 24-48 hours), after 2-4 weeks after vaccination - benign serocious meningitis (each case of serous meningitis requires differential diagnosis).

CONTRAINDICATIONS
Hypersensitivity (including gentamycin and chicken protein), primary immunodeficiency, malignant blood diseases and neoplasms, severe reaction (hyperthermia above 40 degrees C, hyperemia or swelling more than 8 cm in diameter at the site of administration) or complication of the previous introduction mumps or measles vaccines, acute infectious and non-infectious diseases or exacerbation of chronic diseases (vaccination postponed until recovery or remission), pregnancy.

PREGNANCY AND LACTATION
Contraindicated in pregnancy.

SPECIAL INSTRUCTIONS
HIV infection is not a contraindication for vaccination.


With moderate forms of acute respiratory viral infection, acute intestinal diseases, vaccination is carried out immediately after the normalization of body temperature.


Vaccination is not recommended during the period of rising incidence of serous meningitis.


Vaccination is performed no earlier than 3-6 months after the end of immunosuppressive therapy.


Vaccination can be performed simultaneously (one day) with other calendar vaccinations (against polio, hepatitis B, pertussis, diphtheria, tetanus) or not earlier than 1 month after the previous vaccination;
after the introduction of human Ig - no earlier than 2 months, and after vaccination with mumps vaccine, Ig administration is allowed only after 2 weeks. If Ig is needed before this time, vaccination against mumps and measles should be repeated.

Persons temporarily released from vaccination should be monitored and vaccinated after withdrawal of contraindications.


Febrile convulsions in the anamnesis, as well as hyperthermia over 38.5 degrees C in the post-vaccination period are an indication for the appointment of antipyretic drugs.


Immediately before the introduction, the vaccine is diluted with a diluent for measles, parotitic and parotitic measles live live vaccines at a rate of 0.5 ml of solvent per inoculum dose of the vaccine.
The vaccine should completely dissolve within 3 minutes.

Vaccine or solvent in ampoules with broken integrity, marking, and also at change of their physical properties (color and transparency, etc.), with expired shelf life or incorrectly stored are not suitable for use.


Opening of ampoules and the vaccination procedure are carried out with strict adherence to aseptic and antiseptic rules.


Ampoules with a vaccine and a solvent at the incision site are treated with 70 deg.
ethanol and break, while not allowing the ingress of ethanol into the ampoule.

To dilute the vaccine, take all the necessary volume of the solvent and transfer it to an ampoule with a dry vaccine.
After mixing, the vaccine is taken up by another needle in a sterile syringe and used for vaccination.

The dissolved vaccine is used immediately and is not subject to storage.


Vaccination is recorded in the prescribed registration forms with the name of the drug, the date of vaccination, dose, manufacturer, serial number, date of manufacture, expiration date, response to vaccination.

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