Universal reference book for medicines
Product name: BELLALGIN (BELLALGIN)

Active substance: comb.
drug
Type: The drug with m-cholinoblock, antacid and analgesic action

Manufacturer: TATHIMFARMPREPARATY (Russia)
A typical clinical and pharmacological article
This information is a reference and it is not enough that the drug has been prescribed by a doctor ..

PHARMACHOLOGIC EFFECT
Combined drug, has antispasmodic, antacid, local anesthetic and analgesic effect.

INDICATIONS
As a symptomatic means for eliminating the pain syndrome in gastrointestinal diseases, accompanied by increased secretion of gastric juice and spasms of smooth muscles:

- Hyperacid gastritis;

- Stomach ulcer and duodenal ulcer;

- Heartburn, eructation;

- gastralgia;

- Spastic colitis;

- Spasm of smooth muscles of the digestive tract.

DOSING MODE
Inside, before meals, 1 tab.
2-3 times / day.
The highest single dose for adults is 3 tablets, daily - 10 tablets.
The duration of treatment is determined by the doctor.
SIDE EFFECT
From the urinary system: a violation of kidney function, oliguria, anuria, proteinuria, interstitial nephritis, urine staining in red.

Allergic reactions: urticaria (including conjunctiva and mucous membranes of the nasopharynx), angioedema, in rare cases - malignant exudative erythema (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome), bronchospastic syndrome, anaphylactic shock.

On the part of the organs of hematopoiesis: agranulocytosis, leukopenia, thrombocytopenia.

Other: decreased blood pressure, dry mouth, thirst, constipation, mydriasis, paresis of accommodation, temporary visual impairment, dysuria, urinary retention, palpitation, drowsiness, dizziness, psychomotor agitation, convulsions.

CONTRAINDICATIONS
hypersensitivity;

- an angle-closure glaucoma;

- hyperplasia of the prostate;

- oppression hemopoiesis (granulocytopenia, leukopenia, agranulocytosis, cytostatic or infectious neutropenia);

- severe hepatic and / or renal insufficiency;

- hereditary hemolytic anemia associated with a deficiency of glucose-6-phosphate dehydrogenase;

- Aspirin asthma;

- Pregnancy (especially in the first trimester and in the last 6 weeks);

lactation period.

With caution: kidney disease (pyelonephritis, glomerulonephritis, including in the anamnesis), prolonged abuse of ethanol.

PREGNANCY AND LACTATION
Contraindications: pregnancy (especially in the first trimester and in the last 6 weeks), lactation period.

APPLICATION FOR FUNCTIONS OF THE LIVER
Contraindication is severe renal failure.

C with caution: kidney disease (pyelonephritis, glomerulonephritis, including in the anamnesis).

APPLICATION FOR VIOLATIONS OF THE FUNCTION OF KIDNEYS
Contraindications - severe hepatic insufficiency.

SPECIAL INSTRUCTIONS
Avoid use of the drug for people whose activities require increased visual acuity.

In the treatment of patients receiving cytotoxic drugs, metamizole sodium should be administered only under medical supervision.

Patients with atopic bronchial asthma and pollinosis have an increased risk of developing allergic reactions.

Against the background of taking metamizole sodium, the development of agranulocytosis is possible, in connection with which, when an unmotivated rise in temperature, chills, sore throats, difficulty swallowing, stomatitis, as well as in the development of the phenomena of vaginitis or proctitis, immediate withdrawal of the drug is necessary.

With prolonged use, it is necessary to monitor the picture of peripheral blood.

It is inadmissible to use to relieve acute pain in the abdomen (until the cause is clarified).

Against the backdrop of treatment, it is possible to stain urine in red due to the release of a metabolite (it does not matter).

OVERDOSE
Symptoms: nausea, vomiting, gastralgia, oliguria, hypothermia, decreased blood pressure, tachycardia, dyspnea, tinnitus, drowsiness, delirium, impaired consciousness, acute agranulocytosis, hemorrhagic syndrome, acute renal and / or hepatic insufficiency, convulsions, respiratory muscle paralysis.

Treatment: gastric lavage, saline laxatives, activated charcoal;
carrying out forced diuresis, hemodialysis, with the development of convulsive syndrome - intravenous diazepam and high-speed barbiturates.
DRUG INTERACTION
Enhances the effects of ethanol.

Simultaneous use with chlorpromazine or other phenothiazine derivatives can lead to the development of severe hyperthermia.

Radiopaque drugs, colloidal blood substitutes and penicillin should not be used during treatment with metamizole.

With the simultaneous use of cyclosporine, the concentration of the latter in the blood decreases.

Metamizole, displacing from the bond with protein oral hypoglycemic drugs, indirect anticoagulants, GCS and indomethacin, increases their activity.

Phenylbutazone, barbiturates and other hepatoinductors with simultaneous administration reduce the effectiveness of metamizole.

Simultaneous reception with other non-narcotic analgesics, tricyclic antidepressants, hormonal contraceptives and allopurinol may lead to increased toxicity.

Sedative and anxiolytic drugs (tranquilizers) increase the analgesic effect of metamizole.

Thiamazole and cytostatics increase the risk of developing leukopenia.

The effect is enhanced by codeine, histamine H 2 -receptor blockers and propranolol (slows inactivation).

TERMS OF RELEASE FROM PHARMACY
The drug is approved for use as a means of OTC.

TERMS AND CONDITIONS OF STORAGE
Keep in a dry place, protected from light and out of the reach of children.

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