Composition, form of production and packaging
? Cream for external use 0.05% white or almost white.
100 g
betamethasone dipropionate 64 mg,
which corresponds to the content of betamethasone 50 mg
Auxiliary substances: methyl parahydroxybenzoate 0.2 g, paraffin solid 9 g, petrolatum 3 g, propylene glycol 5 g, liquid paraffin 18 g, emulsion wax 7 g, disodium edetate 0.1 g, sodium sulfite 0.05 g, purified water - up to 100 g.
15 g - aluminum tubes (1) - cardboard packs.
30 g - aluminum tubes (1) - cardboard packs.
50 g - aluminum tubes (1) - packs of cardboard.
? Ointment for external use 0.05% from white to white with a yellowish tint of color, translucent.
100 g
betamethasone dipropionate 64 mg,
which corresponds to the content of betamethasone 50 mg
Excipients: propyl parahydroxybenzoate - 0.05 g, liquid paraffin (vaseline oil) - 4 g, isopropyl myristate - 1 g, vaseline - up to 100 g.
15 g - aluminum tubes (1) - cardboard packs.
30 g - aluminum tubes (1) - cardboard packs.
INSTRUCTION FOR THE SPECIALIST.
The product description was approved by the manufacturer for the 2009 print edition.
PHARMACHOLOGIC EFFECT
GCS, has anti-inflammatory, antipruritic and vasoconstrictive effect.
INDICATIONS
- allergic skin diseases (including acute, subacute and chronic contact dermatitis, occupational dermatitis, sun dermatitis, neurodermatitis, skin itching, dyshidrotic dermatitis);
- acute and chronic forms of non-allergic dermatitis;
- psoriasis.
DOSING MODE
Acriderm should be applied a thin layer on the affected areas 1-3 times / day, slightly rubbing. The duration of treatment should not exceed 3 weeks.
The use of Acryderm in children under the age of 12 years is carried out under the supervision of a doctor.
SIDE EFFECT
Possible: burning, irritation and dry skin, folliculitis, hypertrichosis, hypopigmentation, allergic contact dermatitis, skin atrophy, striae and sweating. In case of side effects, consult a doctor.
CONTRAINDICATIONS
- Tuberculosis of the skin;
- viral skin infections;
- vaccination;
- perioral dermatitis;
- pink acne (rosacea);
- hypersensitivity to any component of the drug.
PREGNANCY AND LACTATION
Due to the fact that the safety of the use of local GCS in pregnant women has not been established, the use of drugs of this class during pregnancy is justified only if the benefit to the mother clearly exceeds the possible harm to the fetus. Drugs of this group can not be used in pregnant women in large doses for a long time.
Since it has not been established to date whether glucocorticosteroids can be absorbed into breast milk by topical application and systemic absorption, a decision should be made whether to stop breastfeeding or to abolish the drug, given the need for its use for the mother.
APPLICATION FOR CHILDREN
Children may be more susceptible to the use of local SCS, which causes oppression of the hypothalamic-pituitary-adrenal system (GGN) than older patients, due to increased absorption of the drug, associated with a greater ratio of their surface area and body weight. Children who took local SCS had the following side effects: suppression of the function of the system's GGN, Cushing's syndrome, linear growth retardation, lag in weight gain, increased intracranial pressure. Symptoms of oppression of the adrenal cortex in children include a decrease in the level of cortezol in the plasma and a lack of response to stimulation of ACTH. Increase in intracranial pressure is manifested by bulging fontanel, headache, bilateral edema of the optic disc.
SPECIAL INSTRUCTIONS
In the absence of the effect of treatment for two weeks, it is recommended to consult a doctor in order to clarify the diagnosis. If there is irritation or an increased sensitivity reaction when using the drug, the treatment should be stopped and consulted by your doctor. In secondary fungal or bacterial infection, appropriate medicines should be used. In the absence of a quick positive effect, the use of Acriderm should be stopped until all signs of infection are eliminated.
It is not recommended to use the product on the face for a long time. Do not use Acriderm in the eye area, because in this case, the development of cataracts, glaucoma, fungal infection and exacerbation of herpetic infection.
Use in Pediatrics
Children may be more susceptible to the use of local SCS, which causes oppression of the hypothalamic-pituitary-adrenal system (GGN) than older patients, due to increased absorption of the drug, associated with a greater ratio of their surface area and body weight. Children who took local SCS had the following side effects: suppression of the function of the system's GGN, Cushing's syndrome, linear growth retardation, lag in weight gain, increased intracranial pressure. Symptoms of oppression of the adrenal cortex in children include a decrease in the level of cortezol in the plasma and a lack of response to stimulation of ACTH. Increase in intracranial pressure is manifested by bulging fontanel, headache, bilateral edema of the optic disc.
OVERDOSE
Symptoms: Excessive or prolonged use of local SCS can cause oppression of the pituitary-adrenal system, which can lead to secondary adrenocortical insufficiency and the emergence of symptoms of hypercortisy, including Cushing's syndrome.
Treatment: the appropriate symptomatic treatment is indicated. Acute symptoms of hypercorticoidism are usually reversible. If necessary, correction of electrolyte imbalance is shown. In the case of chronic toxic effects, gradual cancellation of GCS is recommended.
DRUG INTERACTION
There were no clinically significant interactions with other drugs.
TERMS OF RELEASE FROM PHARMACY
The drug is approved for use as a means of OTC.
TERMS AND CONDITIONS OF STORAGE
The drug should be stored out of reach of children at a temperature of 15 to 25 В° C. Shelf life - 2 years.
