Description of the active substance :.
This information is a reference and it is not enough that the drug was prescribed by a doctor. .
PHARMACHOLOGIC EFFECT
Sodium and chlorine ions are the most important inorganic components of the extracellular fluid, supporting the corresponding osmotic pressure of blood plasma and extracellular fluid. Isotonic solution replenishes fluid deficiency in the body during dehydration. Hypertensive sodium chloride solution with IV administration provides correction of osmotic pressure of extracellular fluid and blood plasma. With topical application in ophthalmology sodium chloride has anti-edematous effect.
INDICATIONS
Isotonic solution: dehydration of various genesis. To maintain the volume of blood plasma during and after operations. As a solvent for various drugs.
Hypertonic solution: disturbances of water-electrolyte metabolism: deficiency of sodium and chlorine ions; hypoosmolar dehydration of various genesis (due to prolonged vomiting, diarrhea, burns, with gastric fistula, pulmonary hemorrhage, intestinal bleeding).
Eye drops and ointment: irritation of the cornea in inflammatory and allergic diseases (in combination therapy).
DOSING MODE
Isotonic sodium chloride solution is administered IV, SC and in enemas, and also used for washing wounds, eyes, mucous nasal cavity. It is often administered IV, depending on the clinical situation - up to 3 liters / day.
Hypertensive sodium chloride solution is administered iv. A single dose for IV injection may be 10-30 ml. In conditions requiring immediate replenishment of sodium and chlorine ions, the drug is administered intravenously drip in a dose of 100 ml.
Locally and externally apply depending on the dosage form used and the treatment regimen.
SIDE EFFECT
Possible: nausea, vomiting, diarrhea, stomach cramps, thirst, lacrimation, sweating, fever, tachycardia, arterial hypertension, impaired renal function, swelling, shortness of breath, headache, dizziness, anxiety, weakness, twitching and hypertonic muscle.
With external and local application, adverse reactions have not been established to date.
CONTRAINDICATIONS
Hypernatremia, hyperhydration states, threat of pulmonary edema, brain.
APPLICATION FOR FUNCTIONS OF THE LIVER
Caution is used large volumes of sodium chloride in patients with impaired renal excretion.
SPECIAL INSTRUCTIONS
With caution apply large volumes of sodium chloride in patients with impaired renal excretory function, with hypokalemia. The introduction of large amounts of solution can lead to chloride acidosis, hyperhydration, an increase in the excretion of potassium from the body.
Hypertonic solution is not applied sc and v / m.
With prolonged use, it is necessary to monitor the concentration of electrolytes in plasma and daily diuresis.
The temperature of the infusion solution should be 38 В° C.
