Universal reference book for medicines
Product name: ADRIANOL ® (ADRIANOL ® )

Active substance: lerimazoline, phenylephrine

Type: Vasoconstrictive drug for topical application in ENT practice

Manufacturer: FHI ZDRAVLJE AD LESKOVAC (Serbia)
Composition, form of production and packaging
? Nasal drops (for children) in the form of a clear, colorless or slightly yellowish solution.
1 ml
phenylephrine hydrochloride 0.5 mg
Lerimazoline hydrochloride 0.5 mg
Excipients: methylcellulose MNV 10000 - 1.32 mg, benzalkonium chloride 0.2 mg, glycerol 0.015 mg, citric acid monohydrate 5.72 mg, sodium hydrogen phosphate dihydrate 8.11 mg, purified water up to 1 ml.
10 ml - a bottle-droppers polyethylene (1) - packs cardboard.
? Nasal drops in the form of a clear, colorless or slightly yellowish solution.
1 ml
phenylephrine hydrochloride 1 mg
LYRIMAZOLINE hydrochloride 1.5 mg
Excipients: methylcellulose MNV 10000 - 2.9 mg, benzalkonium chloride 0.2 mg, glycerol 0.03 mg, citric acid monohydrate 5.72 mg, sodium hydrogen phosphate dihydrate 8.11 mg, purified water up to 1 ml.
10 ml - a bottle-droppers polyethylene (1) - packs cardboard.
INSTRUCTION FOR THE SPECIALIST.
Description of the drug approved by the manufacturer for the printed edition of 2016.
PHARMACHOLOGIC EFFECT
Phenylephrine and Lerimazoline are vasoconstrictors that have an anti-edematous effect on the nasal mucosa during topical application. Reducing the edema of the mucosa leads to a normalization of nasal breathing and a decrease in the pressure in the paranasal sinuses and the middle ear. The viscous consistency of the solution increases the duration of the action of the preparation.
INDICATIONS
- Acute and chronic rhinitis, sinusitis;
- is used as an auxiliary decongestant during diagnostic procedures and surgical manipulations.
DOSING MODE
Children from 3 years (drops nasal for children): 2 drops in each nasal passage 3 times a day.
Adults and children from 7 years (drops nasal): 1-3 drops in each nasal passage 4 times a day.
Duration of the drug - no more than 1 week, then a break for several days is necessary.
SIDE EFFECT
Local reactions: burning, soreness or dryness of the mucous membrane of the nose, swelling of the mucous membrane of the nasal cavity, abundant discharge, violation of taste sensitivity.
Systemic reactions: nausea, dizziness, headache, tachycardia, increased blood pressure, allergic reactions.
With prolonged use: rhinitis, nasal congestion, atrophy of the nasal mucosa.
CONTRAINDICATIONS
- increased individual sensitivity;
- thyrotoxicosis;
- pheochromocytoma;
- glaucoma;
- severe kidney damage;
- arterial hypertension;
- cardiac ischemia;
- Atrophic rhinitis;
- common atherosclerosis;
- Children under 3 years of age (nasal drops for children);
- Children under 7 years.
APPLICATION FOR FUNCTIONS OF THE LIVER
Adrianol can not be used for severe kidney damage.
APPLICATION FOR CHILDREN
Children from 3 years (for the drug in the drug form, nasal drops for children): 2 drops in each nasal passage 3 times a day.
SPECIAL INSTRUCTIONS
Do not use simultaneously with MAO inhibitors and within 10 days after the end of their use.
With prolonged use, the severity of the vasoconstrictor effect gradually decreases (the phenomenon of tachyphylaxis), therefore, should not be used for a long time, for example, in chronic rhinitis.
OVERDOSE
Symptoms: fatigue, dizziness, nausea, insomnia, increased blood pressure, tachycardia, fever, shock, reflex bradycardia.
DRUG INTERACTION
In combination with antidepressants and MAO inhibitors, the risk of hypertension increases.
TERMS OF RELEASE FROM PHARMACY
The drug is approved for use as a means of OTC.
TERMS AND CONDITIONS OF STORAGE
Store in a dry place, protected from light, out of reach of children, at a temperature of no higher than 25 ° C.
Shelf life - 3 years. Do not use after expiry date.
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