Universal reference book for medicines
Product name: AGIOLAX (AGIOLAX)

Active substance: Ispaghula hask, Plantago ovata, Senna

Type: Laxative phytopreparation

Manufacturer: MADAUS (Germany)
Composition, form of production and packaging
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Granules for oral administration 100 g
Powder coat seed psyllium oval 2.2 g

oval seed plantain seed 52g

powder of Senna narrow-leaved fruit 6.74-13.15 g

100 g - containers.

250 g - containers.

INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2010.

PHARMACHOLOGIC EFFECT

Laxative.
Seeds and seed peel of plantain, binding to water, swell, increase the volume of contents of the intestine and, as a result of mechanical stimulation of the intestinal receptors, increase its peristalsis. Active substances from senna fruits chemically irritate the receptors of the intestinal mucosa and reflexively enhance its peristalsis. As a result of increased secretion of mucins, the fecal masses soften and facilitate their progress. The medicinal form of the preparation in the form of granules ensures the gradual release of active substances, which allows to avoid the rapid achievement of high concentrations of sennosides. Laxative action occurs after 8-12 hours.
INDICATIONS

- constipation due to hypo-, atony of the colon (including hypodynamia, prolonged immobilization, postoperative period).

- regulation of stool with hemorrhoids, proctitis, anal fissures.

DOSING MODE

Inside, not liquid, squeezed with enough water (about 250 ml).

Adults and children over 10 years: 1 teaspoonful each evening before bedtime and, if necessary, in the morning before breakfast.

SIDE EFFECT

Allergic reactions are possible.
The laxative effect of the drug may be accompanied by colic pain in the abdomen, flatulence. With long-term use, especially in high doses, it is possible: loss of electrolytes (mainly potassium), proteinuria, hematuria.
CONTRAINDICATIONS

- deficiency of sugar / isomaltase;

- intolerance to fructose;

- glucose-galactose malabsorption (because the dosage form contains sucrose);

- intestinal obstruction;

- Spastic constipation;

- strangulated hernia;

- Acute inflammatory diseases of the abdominal cavity organs (including peritonitis, appendicitis, Crohn's disease and ulcerative colitis);

- gastrointestinal and uterine bleeding;

- Cystitis;

- Violations of water-electrolyte exchange;

Decompensated diabetes mellitus;

- children's age till 10 years;

- Hypersensitivity to the components of the drug.

With caution: prescribe for diseases of the liver and / or kidneys, compensated for diabetes (because the dosage form contains sucrose), as well as in the I trimester of pregnancy and during lactation.
In the II and III trimesters of pregnancy, the drug is administered under medical supervision.
PREGNANCY AND LACTATION

With caution: in the first trimester of pregnancy and during lactation.
In the II and III trimesters of pregnancy, the drug is administered under medical supervision.
APPLICATION FOR FUNCTIONS OF THE LIVER

With caution: with kidney disease.

APPLICATION FOR VIOLATIONS OF THE FUNCTION OF KIDNEYS

With caution: with liver diseases.

APPLICATION FOR CHILDREN

Contraindicated for children under 10 years.

SPECIAL INSTRUCTIONS

It is not recommended to use the drug for more than 2 weeks.

Patients with diabetes should take into account that the maximum content of sucrose in 5 g of the drug is 1.2 g, which corresponds to 0.1 grain unit.

The drug should be used in case you can not achieve the effect by changing the diet.

There is no influence on the ability to drive vehicles and manage mechanisms.

OVERDOSE

In cases of overdose, cramping abdominal pain, diarrhea, and, as a result, a disturbance of water-electrolyte metabolism may occur. In case of an overdose, immediately consult a doctor.

DRUG INTERACTION

With long-term use of the drug in high doses, it is possible to develop hypokalemia, which can lead to an increase in the action of cardiac glycolisoids and affect the effect of antiarrhythmic drugs.

The risk of hypokalemia also increases with the simultaneous use of the drug Agiolax with thiazide diuretics, glucocorticosteroids, licorice root preparations.

TERMS OF RELEASE FROM PHARMACY

On prescription.

TERMS AND CONDITIONS OF STORAGE

At a temperature of no higher than 30 ° C.
Keep out of the reach of children. Shelf life - 3 years.

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